Recombinant CD52 (Alemtuzumab Biosimilar) 抗体
Quick Overview for Recombinant CD52 (Alemtuzumab Biosimilar) 抗体 (ABIN7795101)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
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Expression System
- Mammalian cells
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原理
- Alemtuzumab Biosimilar, Human CD52 Monoclonal Antibody
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产品特性
- Alemtuzumab Biosimilar uses the same protein sequences as the therapeutic antibody alemtuzumab. Alemtuzumab is a medication used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. In CLL, it has been used as both a first line and second line treatment. In MS it is generally only recommended if other treatments have not worked. It is given by injection into a vein. It is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD52
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD52 (Alemtuzumab Biosimilar)
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别名
- Alemtuzumab Biosimilar
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物质类
- Biosimilar
抗原
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